Search on: MEDIATOR COMPLEX SUBUNIT 1 
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Descriptor English:   Mediator Complex Subunit 1 
Descriptor Spanish:   Subunidad 1 del Complejo Mediador 
Descriptor Portuguese:   Subunidade 1 do Complexo Mediador 
Tree Number:   D05.500.374.750
D12.644.360.024.304.750
D12.644.360.024.308.049
D12.776.157.057.062.750
D12.776.157.057.080.049
D12.776.476.024.388.750
D12.776.476.024.394.049
D12.776.660.551.750
D12.776.660.675.049
D12.776.930.617.049
Definition English:   A mediator complex subunit that is believed to play a key role in the coactivation of nuclear receptor-activated transcription by the mediator complex. It interacts with a variety of nuclear receptors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; VITAMIN D RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; ESTROGEN RECEPTORS; and GLUCOCORTICOID RECEPTORS. 
History Note English:   2010(1998) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   53576 
Unique Identifier:   D056913 

Occurrence in VHL:
 

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